[Main ingredient] Flunixin meglumine

【 Appearance 】 This product is a colorless or light yellow clear liquid.

Pharmacological effects: Flunixin meglumine is a potent cyclooxygenase inhibitor with analgesic, antipyretic, anti-inflammatory, and anti rheumatic effects. The analgesic effect is caused by inhibiting the synthesis of peripheral prostaglandins or their pain sensitizers, or their combined action, thereby blocking the transmission of pain impulses. The anti-inflammatory effect of peripheral tissues may be caused by inhibiting cyclooxygenase, reducing the formation of prostaglandin precursors, and inhibiting other mediators to induce local inflammatory responses. After a single intramuscular injection in pigs (2.2 mg/kg body weight), the plasma elimination half-life is 3-4 hours, the peak concentration is 2.94 μ g/mL, and the peak time is 0.4 hours. The drug can still be detected in the blood 18 hours after administration. The apparent distribution volume is 2.0 L/kg, and the bioavailability of a single neck injection is 87%.

Drug Interactions

(1) Flunixin meglumine should not be used in combination with other nonsteroidal anti-inflammatory drugs, as it can exacerbate the toxic side effects on the gastrointestinal tract, such as ulcers, bleeding, etc.

(2) Due to the high binding rate of plasma proteins, when used in combination with other drugs, flunixin meglumine may displace other drugs that bind to plasma proteins or be replaced by other drugs, resulting in enhanced effects and even toxicity of the displaced drugs.

(3) Combined with antibiotics, it is used as an adjuvant therapy for the absence of milk syndrome in sows.

[Function and Use] Antipyretic, analgesic, and anti-inflammatory drugs. Used for fever, inflammatory diseases, muscle pain, and soft tissue pain in livestock and small animals.

[Usage and Dosage] Intramuscular injection: One dose, 0.4ml per 10kg body weight for beef cattle and pigs; Dogs and cats 0.2~0.4ml. 1-2 times a day, for no more than 5 consecutive days.

【 Adverse reactions 】 Intramuscular injection has a stimulating effect on the local area. Long term high-dose use of this product may lead to gastric ulcers and kidney function damage in animals.

[Precautions] Use with caution in livestock with digestive ulcers.

[Rest period] 28 days for cattle and pigs.

【 Specification 】 Calculated based on C14H11F3N2O2 50ml: 2.5g

[Packaging] 50ml/bottle, 60 bottles/box

[Storage] Store in a dark and sealed environment.

【 Validity Period 】 2 years

[Approval number] Veterinary drug number 170612103

Wuhan Liyao Pharmaceutical Co., Ltd